areas of research

OCCUPANCY/FUNCTION MEASUREMENTS AND MODELS USING SIMULTANEOUS PET/FMRI

Fig 3. Parametric maps showing the results from three injection doses of the dopamine agonist quinpirole. CBV, cerebral blood volume; DBP, dynamic-binding potential.

Development and characterization of IRON fMRI

Fig 2. An average image of the relative blood volume fraction in rat brain calculated as the negative log ratio of the signal attenuation produced by injection of MION contrast agent.

Development and application of pharmacological fMRI

Fig 5. BOTTOM: Temporal responses in caudate for 4 injections of remifentanil and 2 injections of morphine.

Contributions to fMRI physiology

Fig 1. Functional images of cocaine-induced brain activation sequentially obtained in the same animals (N = 5) using the BOLD method (a) or the CBV method (b)

Development of fMRI in awake behaving NHP

Fig X.